What you'll learn
Define the physicochemical properties of the drug substance
Evaluate the physicochemical properties according to desired dosage form
Understand to scientific and technological aspects of the design, compounding, and manufacture of dosage forms
Explain solubility, permeability, ionization constant, crystal, polymorph, amorph, particle size, particle shape, surface area and bulk/tapped density
Requirements
Require mobile/tablet/laptop/personal computer with internet
To be student, graduate and/or pharma professional
Description
Preformulation studies are very important for the development of a pharmaceutical dosage forms in the pharmaceutical industry. This course will help you to understand preformulation development approach with basic concepts of preformulation studies of the Pharma Industry. Each drug substance has intrinsic chemical and physical characteristics that must be considered before the development of a pharmaceutical formulation. Drug product is formulated using the information gained during the preformulation studies and with the consideration of the dose or doses, dosage form, and route of administration desired for the clinical studies and for the proposed marketed product. Pharmaceutics includes the scientific and technological aspects of the design, compounding, and manufacture of dosage forms. In the scope of this course, most important physicochemical properties of the drug substance such as solubility, permeability, ionization constant, crystality, polymorphism, amorphous, particle size, particle shape, particle surface area and bulk tapped density & flow evaluation have been discussed.These aspects in the design of dosage forms are discussed in the scope of this course.COURSE CONTENTPhysicochemical Properties of the Drug SubstanceTopic 1: SolubilityTopic 2: PermeabilityTopic 3: Ionization ConstantTopic 4: CrystalityTopic 5: PolymorphismTopic 6: AmorphousTopic 7: Particle SizeTopic 8: Particle ShapeTopic 9: Particle Surface AreaTopic 10: Bulked Tapped Density & Flow Evaluation
Overview
Section 1: INTRODUCTION
Lecture 1 WELCOME!
Section 2: CHEMICAL AND PHYSICAL PROPERTIES OF DRUG SUBSTANCE
Lecture 2 SOLUBILITY
Lecture 3 PERMEABILITY
Lecture 4 IONIZATION CONSTANT
Lecture 5 CRYSTALITY, POLYMORPHISM, AMORPHOUS
Lecture 6 PARTICLE SIZE, PARTICLE SHAPE, SURFACE AREA
Lecture 7 BULK TAPPED DENSITY, FLOW PROPERTIES
Section 3: CONCLUSION
Lecture 8 THANK YOU!
Anyone who is looking to get entry in pharmaceutical industry,Existing pharma professionals who are looking to progress in their jobs



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